impact of opium on the serum levels of tgf-β in diabetic, addicted and addicted-diabetic rats
نویسندگان
چکیده
background: several cells of immune system such as regulatory t cells and macrophages secrete transforming growth factor-β (tgf-β) in response to different stimuli. this cytokine has inhibitory effect on immune system and diminished production of this cytokine is associated with autoimmune disorders. objective: the aim of this study was to evaluate the influence of opium addiction on serum level of tgf-β in male and female diabetic and non-diabetic wistar rats. methods: this experimental study was performed on normal, opium addicted, diabetic and addicted-diabetic male and female rats. serum level of tgf-β was measured by elisa. results: the results of our study indicated that the mean serum level of tgf-β in female addicted rats was significantly increased compared to control group (p
منابع مشابه
Impact of Opium on the Serum Levels of TGF-β in Diabetic, Addicted and Addicted-Diabetic Rats
Background: Several cells of immune system such as regulatory T cells and macrophages secrete transforming growth factor-β (TGF-β) in response to different stimuli. This cytokine has inhibitory effect on immune system and diminished production of this cytokine is associated with autoimmune disorders. Objective: The aim of this study was to evaluate the influence of opium addiction on serum leve...
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عنوان ژورنال:
iranian journal of immunologyجلد ۷، شماره ۳، صفحات ۱۸۶-۱۹۲
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